Egypt develops own vaccine as global flu wave spreads
CAIRO, Monday
Egypt is developing its own vaccine against H1N1 swine flu for production in 2011 and, in the meantime, will import vaccines to inoculate school children and key public workers, the health minister said.
Experts fear a flu pandemic could have a devastating impact on Egypt, a country of 77 million people who mostly live in the densely packed Nile Valley. Many are in Cairo’s crowded slums.
Egypt, already hard hit by the more deadly H5N1 bird flu virus, has found about 1,030 cases of H1N1 flu, widely known as swine flu, and three people have died from the virus, Health Minister Hatem el-Gabali said late on Sunday.
“We have a plan to produce the first batch (of Egypt’s H1N1 flu vaccine) by April 2011,” Mr Gabali said, speaking after a talk about healthcare reform.
A 35-strong team of experts had been assembled from around Egypt to develop the vaccine, the minister told Reuters.
“We are working now in the lab,” he said. “They (the team) were people working in independent institutions, around Egypt. They have trained overseas but they have not worked together as a team. They have the skills to develop the vaccine.”
“The production (of) the first batch will be about 6,000 units and it will be tested for efficacy around the second quarter of 2011,” he said.
Output from the factory, to be built in Sixth of October City on the outskirts of Cairo, would meet demand in Egypt but could also supply other countries in Africa, he said.
Other countries, including developing nations, are also working to produce their own vaccines in expectation that global supplies from pharmaceutical giants like GlaxoSmithKline and Novartis will be quickly spoken for.
The World Health Organisation has given Egyptian national producer Vacsera a seed grant and technical guidance to ramp up its capacity to eventually make flu vaccine.
“We are working closely with the WHO and they want us to expand our capacity and we will do that,” Mr Gabali said.
In the meantime, Mr Gabali said Egypt had contracted to buy about 5 million vaccines and requested that the WHO provide 15 million from its stock, with an additional 5 million vaccines coming from the private sector.
He spoke of vaccinating a total of 30 million people. “My target is to vaccinate all the students, which are about 20 million, and then the rest of the 10 million will be those in critical jobs that affect the public life daily.”
Mr Gabali said the focus would be school children from kindergarten age to secondary school.
WHO said today about 100 low- and middle-income nations would receive H1N1 flu vaccines donated by firms such as GlaxoSmithKline and Sanofi.
Vaccines could be sent as early as next month, it said.
Improve hygiene
Egypt has stepped up surveillance at airports to detect anyone arriving with H1N1 flu and put in place measures to trace them if they fall ill during their stay.
It has also campaigned to improve hygiene at schools, which opened late this year.
WHO plans to start sending H1N1 flu vaccines to poorer countries as early as next month, the UN agency’s head of vaccine research said today.
Ms Marie-Paule Kieny said: “We are trying to have a first delivery starting in November,” she told journalists in Geneva. “The idea is to start with northern hemisphere countries first.”
The WHO declared in June that a full pandemic was under way from the virus widely known as swine flu.
It has killed at least 4,500 people so far but caused mainly mild to moderate effects in most patients as it spread around the world.
Ms Kieny said it was critical that health workers in poorer countries get protected against the virus to avoid passing it to the patients they treat and to ensure that hospitals and health clinics can stay open throughout an outbreak.
China began the world’s first mass vaccination programme in late September, followed by Australia and the United States.
Ms Kieny said the vaccines that have been quickly developed in response to the H1N1 strain are yielding more volume than first expected, raising hopes about the total quantity of shots that could be made available.
Work is under way to determine the exact production capacity of vaccine manufacturers worldwide, the expert said.
More virulent
She signalled one dose of the vaccine could be enough to ensure protection against the flu strain, which does not appear to have morphed into a more virulent or milder form since its emergence in the United States and Mexico.
“All the data that we have seen show that one dose is sufficient,” she said.
Last week, the UN agency said it could take years for the H1N1 infection rate to slow down.
Once enough people have been exposed to the virus or have gained protection from vaccination, it could act more as a seasonal flu instead of a pandemic one, WHO spokesman Gregory Hartl said. (Reuters)